What distinguishes Behçet disease from isolated recurrent aphthous ulcers?
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What distinguishes Behçet disease from isolated recurrent aphthous ulcers?
Behçet disease is a relapsing multisystem vasculitis. Recurrent oral ulcers may precede genital ulcers, uveitis, skin lesions, arthritis, vascular disease, or neurologic and gastrointestinal involvement. A pathergy response can occur. HLA-B51 is an association, not a diagnostic test on its own.